Cognitive impairment and sedentary behavior predict health-related attrition in a prospective longitudinal Parkinson's disease study
نویسندگان
چکیده
IntroductionIn Parkinson's disease (PD), the high burden of motor and non-motor symptoms, such as cognitive impairment or falls, is associated with rapid progression mortality. This often reflected by an increased drop-out rate PD patients in longitudinal studies. Active physical behavior can impact course beneficially has overall positive effect on health. Contrarily, sedentary PD. The aim this study was to investigate whether assessed home environment predict health-related attrition due sickness death PD.MethodsData 45 patients, longitudinally assessed, were analyzed. Of those, 20 completed six yearly visits, 16 dropped out death, nine for other reasons. All wore a mobile device assess testing.ResultsLogistic regression revealed global cognition primary predictor varying models (p ≤ .04). In survival analysis, = .005) longer mean bout length .02) death. occurrence highest both impaired bouts.ConclusionsCognition However, it seems that might have potential negative influence patients’ health, especially those impairment.
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ژورنال
عنوان ژورنال: Parkinsonism & Related Disorders
سال: 2021
ISSN: ['1353-8020', '1873-5126']
DOI: https://doi.org/10.1016/j.parkreldis.2020.11.015